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KMID : 0360119950170010096
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
1995 Volume.17 No. 1 p.96 ~ p.107
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Comparision of peripheral nerve regeneration following crushing or resection injuries in rat sciatic nerves
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Abstract
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The purpose of this experimental study was to examine and compare the regeneration capacity between crushed nerve & transected nerve.
For this study, 20 Sprague-Dawley female albino rats were used as experimental animals and divided into two groups. In group 1, the sciatic nerves were crushed 6mm. In length for 1 min. using maximum force with a needle holder. In group 2, the
sciatic
nerves were resected 6mm. In length and the gaps were encased by inserting the proximal and distal stumps into each end of silicone tubes.
The animals were sacrificed 1 month & 2 months after the experiment. All specimens were fixed in 2.5% glutaraldehyde and 1% Osmium tetroxide solution then embedded in epon 812 and were cross-sectioned at 1㎛.
After these procedures, specimens were observed under Light microscope.
@ES The results obtained were as follows.
@EN 1. Group 1 showed greter diameters of regenerating nerves than group 2.
2. Group 1 showed greater number of axons than group 2.
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KEYWORD
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